SCHEMBL5481362

SCHEMBL5481362

Cc1cc([Se]C(Cc2ccccc2)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.70
PPARA Q07869 3/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5484281 0.85 PPARD (0.49) PPARDPPARA
SCHEMBL5481423 0.85 PPARD (0.50) PPARDPPARA
SCHEMBL11926063 0.82 PPARD (1.00) PPARDPPARA
SCHEMBL5217114 0.82 PPARD (1.00) PPARDPPARA
SCHEMBL11926058 0.82 PPARD (1.00) PPARDPPARA
SCHEMBL11926061 0.82 PPARD (1.00) PPARDPPARA
SCHEMBL5654333 0.80 PPARD (0.70) PPARDPPARA
SCHEMBL15097176 0.79 PPARD (1.00) PPARDPPARA
SCHEMBL4851656 0.79 PPARD (0.66) PPARDPPARA
SCHEMBL5483798 0.79 PPARD (1.00) PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1841748-B1 ORGANOSELENIUM CONTAINING COMPOUNDS AND THEIR USE SEOUL NAT UNIV IND FOUNDATION (KR) 2011-12-28 EP disclosed
EP-1841748-A1 ORGANOSELENIUM CONTAINING COMPOUNDS AND THEIR USE Kang, Heonjoong (KR) 2007-10-10 EP disclosed
WO-2006071103-A1 ORGANOSELENIUM CONTAINING COMPOUNDS AND THEIR USE KANG HEONJOONG (KR) 2006-07-06 WO disclosed