Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053235 | 0.94 | CYP1A2 (0.37) | CYP1A2CYP2A6 | |
| SCHEMBL5476789 | 0.91 | CYP1A2 (0.39) | CYP1A2CYP2A6MAOAMAOBEGFR | |
| SCHEMBL7054873 | 0.91 | CYP1A2 (0.39) | CYP1A2CYP2A6MAOAMAOBEGFR | |
| SCHEMBL7054155 | 0.88 | CYP1A2 (0.35) | CYP1A2CYP2A6EGFRERBB2 | |
| SCHEMBL7051312 | 0.85 | CYP1A2 (0.36) | CYP1A2CYP2A6EGFRERBB2 | |
| SCHEMBL7055041 | 0.78 | CYP1A2 (0.40) | CYP1A2CYP2A6 | |
| Hydrochloric Acid SCHEMBL7196886 | 0.78 | CYP1A2 (0.40) | CYP1A2CYP2A6 | |
| SCHEMBL8503273 | 0.78 | CYP1A2 (0.40) | CYP1A2CYP2A6 | |
| Hydrochloric Acid SCHEMBL8426784 | 0.78 | CYP1A2 (0.40) | CYP1A2CYP2A6 | |
| SCHEMBL7203717 | 0.75 | CYP1A2 (0.37) | CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160215004-A1 | A NOVEL LIGAND COMPOUND, A PREPARATION METHOD THEREOF, A TRANSITION METAL COMPOUND, AND A PREPARATION METHOD THEREOF | LG CHEM, LTD. (KR) | 2016-07-28 | — | — | US | disclosed |
| US-7241903-B2 | Metallocenes, use in catalyst system for producing olefin polymers | BASELL POLYOLEFINE GMBH (DE) | 2007-07-10 | — | — | US | disclosed |
| EP-1397371-B1 | METALLOCENES AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | BASELL POLYOLEFINE GMBH (DE) | 2006-03-22 | — | — | EP | disclosed |
| US-20040171855-A1 | Metallocenes, use in catalyst system for producing olefin polymers | EQUISTAR CHEMICALS, LP | 2004-09-02 | — | — | US | disclosed |
| EP-1397371-A1 | METALLOCENES AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | Basell Polyolefine GmbH (DE) | 2004-03-17 | — | — | EP | disclosed |
| EP-0985674-B1 | ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS | MITSUBISHI CHEM CORP (JP) | 2003-04-23 | — | — | EP | disclosed |
| WO-2003000706-A1 | METALLOCENES, USE IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | BASELL POLYOLEFINE GMBH (DE) | 2003-01-03 | — | — | WO | disclosed |
| US-6255515-B1 | COORDINATION POLYMERIZATION CATALYSTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-0985674-A1 | ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171855-A1 | Metallocenes, use in catalyst system for producing olefin polymers | H1-4, H1-0, H1-10 | CYP1A2 1305/4885CYP2A6 916/4885MAOA 2313/4885 |
| US-20160215004-A1 | A NOVEL LIGAND COMPOUND, A PREPARATION METHOD THEREOF, A TRANSITION METAL COMPOUND, AND A PREPARATION METHOD THEREOF | CD40LG, OSTC, TNFSF10 | CYP1A2 1129/4885CYP2A6 1587/4885MAOA 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.