SCHEMBL548198

SCHEMBL548198

O=Cc1cc2cc3cc4ccccc4cc3cc2c(C(=O)O)c1C=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C19 P33261 2/20 0.46
HSD17B10 Q99714 2/20 0.46
MEN1 O00255 1/20 0.46
GLA P06280 1/20 0.46
HPGD P15428 1/20 0.46
KMT2A Q03164 1/20 0.46
ERN1 O75460 4/20 0.36
GAA P10253 1/20 0.35
IDO1 P14902 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
DHODH Q02127 1/20 0.32
METAP2 P50579 1/20 0.32
METAP1 P53582 1/20 0.32
TP53 P04637 1/20 0.32
HIF1A Q16665 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL547569 1.00 KDM4E (0.46) KDM4EALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL547540 0.98 KDM4E (0.47) KDM4EALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL2356987 0.86 CYP1A2 (0.59) KDM4EALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL548551 0.81 KDM4E (0.49) KDM4EALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL547879 0.81 KDM4E (0.49) KDM4EALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL547551 0.81 KDM4E (0.45) KDM4EALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL548308 0.80 ERN1 (0.38) KDM4EALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL30103857 0.80 ERN1 (0.38) KDM4EALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL548732 0.80 ERN1 (0.38) KDM4EALDH1A1CYP1A2CYP2C19HSD17B10
SCHEMBL5149391 0.80 KDM4E (0.47) KDM4EALDH1A1CYP1A2CYP2C19HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2080750-B1 RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2020-07-29 EP claimed
EP-2080750-B1 RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2020-07-29 EP disclosed
US-9897913-B2 Radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-02-20 US disclosed
US-20150030980-A1 RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2015-01-29 US disclosed
US-8110334-B2 Radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-02-07 US disclosed
US-20100047709-A1 RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-02-25 US disclosed
EP-2080750-A1 RADIATION-SENSITIVE COMPOSITION Mitsubishi Gas Chemical Company, Inc. (JP) 2009-07-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100047709-A1 RADIATION-SENSITIVE COMPOSITION C1S, C9, RAD51 KDM4E 234/4885ALDH1A1 1078/4885CYP1A2 2215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.