Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527093 | 0.88 | AURKA (0.78) | AURKAAURKB | |
| SCHEMBL4298390 | 0.88 | AURKA (0.85) | AURKAAURKB | |
| SCHEMBL4286638 | 0.87 | AURKA (0.84) | AURKAAURKB | |
| SCHEMBL4295837 | 0.86 | AURKA (0.85) | AURKAAURKB | |
| SCHEMBL4286395 | 0.86 | AURKA (0.87) | AURKAAURKB | |
| SCHEMBL6525973 | 0.85 | AURKA (0.84) | AURKAAURKB | |
| SCHEMBL4286754 | 0.85 | AURKA (0.83) | AURKAAURKB | |
| SCHEMBL5494015 | 0.84 | AURKA (0.87) | AURKAAURKB | |
| SCHEMBL3489016 | 0.84 | AURKA (0.82) | AURKAAURKB | |
| SCHEMBL5497814 | 0.84 | AURKA (0.88) | AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578755-B1 | PHOSPHONOOXY QUINAZOLINE DERIVATIVES AND THEIR PHARMACEUTICAL USE | ASTRAZENECA AB (SE) | 2007-08-22 | — | — | EP | disclosed |
| EP-1578755-A1 | PHOSPHONOOXY QUINAZOLINE DERIVATIVES AND THEIR PHARMACEUTICAL USE | AstraZeneca AB (SE) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004058781-A1 | PHOSPHONOOXY QUINAZOLINE DERIVATIVES AND THEIR PHARMACEUTICAL USE | ASTRAZENECA AB (SE) | 2004-07-15 | — | — | WO | disclosed |