⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24102955 | 0.67 | — | — | |
| SCHEMBL21023684 | 0.63 | — | — | |
| SCHEMBL1384945 | 0.62 | — | — | |
| SCHEMBL21913465 | 0.60 | — | — | |
| SCHEMBL13782775 | 0.58 | — | — | |
| SCHEMBL23183103 | 0.57 | — | — | |
| SCHEMBL20708119 | 0.57 | — | — | |
| SCHEMBL15196963 | 0.57 | — | — | |
| SCHEMBL385192 | 0.56 | — | — | |
| SCHEMBL23766474 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181188-B2 | Aryl ureas as kinase inhibitors | BAYER HEALTHCARE LLC (US) | 2015-11-10 | — | — | US | disclosed |
| US-20120136157-A1 | ARYL UREAS AS KINASE INHIBITORS | DUMAS JACQUES (US) | 2012-05-31 | — | — | US | disclosed |
| EP-1580188-B9 | Aryl ureas as kinase inhibitors | BAYER HEALTHCARE LLC (US) | 2012-05-23 | — | — | EP | disclosed |
| US-8110587-B2 | Antiinflammatory agents; anticancer agents; osteoporosis | BAYER HEALTHCARE LLC (US) | 2012-02-07 | — | — | US | disclosed |
| EP-1580188-B1 | Aryl ureas as kinase inhibitors | BAYER HEALTHCARE LLC (US) | 2011-10-19 | — | — | EP | disclosed |
| EP-1580188-A1 | Aryl ureas as kinase inhibitors | Bayer Pharmaceuticals Corporation (US) | 2005-09-28 | — | — | EP | disclosed |
| EP-1474393-A1 | ARYL UREAS AS KINASE INHIBITORS | Bayer Pharmaceuticals Corporation (US) | 2004-11-10 | — | — | EP | disclosed |
| US-20030216446-A1 | Aryl ureas as kinase inhibitors | BAYER CORPORATION (US) | 2003-11-20 | — | — | US | disclosed |
| WO-2003068746-A1 | ARYL UREAS AS KINASE INHIBITORS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-08-21 | — | — | WO | disclosed |