Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4775098 | 0.95 | PDE10A (0.63) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL4770097 | 0.93 | PDE10A (0.58) | PDE10A | |
| SCHEMBL8225418 | 0.87 | PDE10A (0.66) | PDE10A | |
| SCHEMBL4776422 | 0.73 | PDE10A (0.62) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL4775346 | 0.71 | PDE10A (0.82) | PDE10A | |
| SCHEMBL4794573 | 0.70 | PDE10A (0.49) | PDE10A | |
| SCHEMBL4770279 | 0.69 | PDE10A (0.52) | PDE10A | |
| SCHEMBL5245875 | 0.69 | PDE10A (1.00) | PDE10APDE4APDE4BPDE3BPDE3A | |
| SCHEMBL4741786 | 0.69 | PDPK1 (0.56) | — | |
| SCHEMBL4772441 | 0.68 | PDE10A (0.55) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287707-A1 | Phosphodiesterase 10 inhibitors | MEMORY PHARMACEUTICALS CORPORATION | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287707-A1 | Phosphodiesterase 10 inhibitors | PDE7A, PDE7B, PDE10A | PDE10A 3/4885PDE4A 12/4885PDE4B 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.