SCHEMBL5483736

SCHEMBL5483736

CCOS(=O)(=O)[O-].CC[n+]1ccc(C#N)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 2/20 0.38
CYP2A6 P11509 1/20 0.37
TRPV4 Q9HBA0 1/20 0.35
PGR P06401 2/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
CYP19A1 P11511 1/20 0.33
CA12 O43570 1/20 0.33
ACHE P22303 2/20 0.32
BCHE P06276 1/20 0.32
ELANE P08246 1/20 0.32
HCRTR2 O43614 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
PSMD14 O00487 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10613322 0.85 HDAC8 (0.44) HDAC8CYP2A6CA1CA2CA9
SCHEMBL5487281 0.84 HDAC8 (0.41) HDAC8CYP2A6TRPV4PGRELANE
SCHEMBL17845868 0.81 HTT (0.38) CA1CA2CA9ACHEKDM4E
SCHEMBL28336347 0.80 HDAC8 (0.56) HDAC8CYP2A6CA2CA9CA12
Iodide SCHEMBL10672612 0.78 HDAC8 (0.54) HDAC8CYP2A6CA2CA9CA12
Hydrochloric Acid SCHEMBL8775042 0.78 HDAC8 (0.54) HDAC8CYP2A6CA2CA9CYP19A1
SCHEMBL11758904 0.76 HDAC8 (0.38) HDAC8ACHEKDM4EMEN1PSMD14
SCHEMBL5085627 0.75 KMT2A (0.33) PGRCA1CA2ACHEKDM4E
SCHEMBL5485690 0.72 HDAC8 (0.39) HDAC8KDM4EMEN1PSMD14MAPT
SCHEMBL10340884 0.72 PTPN11 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1854786-A1 Ionic liquids and their use in extraction processes BP p.l.c. (GB) 2007-11-14 EP claimed
EP-1854786-A1 Ionic liquids and their use in extraction processes BP p.l.c. (GB) 2007-11-14 EP disclosed