Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.62 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5484040 | 1.00 | MAPT (0.62) | MAPTCACNA1BAPBA1TSHRALDH1A1 | |
| SCHEMBL36375 | 0.93 | MAPT (0.69) | MAPTCACNA1BAPBA1TSHRALDH1A1 | |
| SCHEMBL36140 | 0.93 | MAPT (0.69) | MAPTCACNA1BAPBA1TSHRALDH1A1 | |
| SCHEMBL36139 | 0.93 | MAPT (0.69) | MAPTCACNA1BAPBA1TSHRALDH1A1 | |
| SCHEMBL6885967 | 0.93 | MAPT (0.69) | MAPTCACNA1BAPBA1TSHRALDH1A1 | |
| SCHEMBL31267242 | 0.93 | TSHR (0.54) | MAPTCACNA1BAPBA1TSHRALDH1A1 | |
| SCHEMBL19273 | 0.93 | — | — | |
| SCHEMBL5167665 | 0.93 | TSHR (0.54) | MAPTCACNA1BAPBA1TSHRALDH1A1 | |
| SCHEMBL2359268 | 0.92 | MAPT (0.55) | MAPTCACNA1BAPBA1TSHRALDH1A1 | |
| SCHEMBL2359270 | 0.92 | MAPT (0.55) | MAPTCACNA1BAPBA1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070281483-A1 | COMPOSITIONS FOR CHEMICAL MECHANICAL POLISHING SILICA AND SILICON NITRIDE HAVING IMPROVED ENDPOINT DETECTION | Rohm and Haas Electronics Materials CMP Holdings, Inc. | 2007-12-06 | — | — | US | disclosed |
| EP-0361685-B1 | Ion exchange resins | ROHM & HAAS (US) | 1994-01-19 | — | — | EP | disclosed |