Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1730010 | 0.92 | F2R (0.59) | F2R | |
| Bromide SCHEMBL5489245 | 0.90 | F2R (0.54) | F2R | |
| Bromide SCHEMBL1728675 | 0.89 | F2R (0.72) | F2RTSHR | |
| SCHEMBL14449099 | 0.88 | F2R (0.71) | F2RTSHR | |
| Bromide SCHEMBL1731180 | 0.84 | F2R (0.72) | F2R | |
| SCHEMBL27505356 | 0.83 | F2R (0.43) | F2R | |
| Bromide SCHEMBL1731432 | 0.83 | F2R (0.80) | F2R | |
| Bromide SCHEMBL1729713 | 0.83 | F2R (0.70) | F2R | |
| Bromide SCHEMBL1731766 | 0.82 | F2R (0.72) | F2R | |
| Bromide SCHEMBL1731452 | 0.82 | F2R (0.52) | F2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007509892-A | — | — | 2007-04-19 | — | — | JP | claimed |
| EP-1678153-A1 | THIOZOLIDINONES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | Schering Aktiengesellschaft (DE) | 2006-07-12 | — | — | EP | claimed |
| WO-2005042505-A1 | THIOZOLIDINONES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-05-12 | — | — | WO | claimed |
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |