Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.63 |
| ▸ | KIT | P10721 | 1/20 | 0.48 |
| ▸ | CKS1B | P61024 | 2/20 | 0.48 |
| ▸ | SKP1 | P63208 | 2/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2533854 | 0.96 | GBA1 (0.67) | GBA1KITCKS1BSKP1SKP2 | |
| SCHEMBL13992531 | 0.83 | GBA1 (0.66) | GBA1KITCKS1BSKP1SKP2 | |
| SCHEMBL31133354 | 0.83 | GBA1 (0.66) | GBA1KITCKS1BSKP1SKP2 | |
| SCHEMBL639540 | 0.83 | GBA1 (0.66) | GBA1KITCKS1BSKP1SKP2 | |
| SCHEMBL31143019 | 0.82 | HTR3B (0.57) | GBA1KITCKS1BSKP1SKP2 | |
| SCHEMBL405743 | 0.82 | HTR3B (0.57) | GBA1KITCKS1BSKP1SKP2 | |
| SCHEMBL16908185 | 0.81 | GBA1 (0.60) | GBA1KITCKS1BSKP1SKP2 | |
| SCHEMBL4013403 | 0.81 | GBA1 (0.51) | GBA1KITCKS1BSKP1SKP2 | |
| SCHEMBL30060994 | 0.81 | POLB (0.47) | GBA1KITCKS1BSKP1SKP2 | |
| SCHEMBL20011912 | 0.81 | POLB (0.47) | GBA1KITCKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007108744-A2 | NOVEL QUINAZOLINES AS 5-HT6 MODULATORS | ASTRAZENECA AB (SE) | 2007-09-27 | — | — | WO | disclosed |