⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812256 | 0.76 | — | — | |
| SCHEMBL10491656 | 0.76 | — | — | |
| SCHEMBL8895945 | 0.72 | — | — | |
| SCHEMBL403755 | 0.69 | — | — | |
| SCHEMBL2358697 | 0.67 | — | — | |
| SCHEMBL7596024 | 0.65 | — | — | |
| SCHEMBL4354453 | 0.65 | — | — | |
| SCHEMBL1122011 | 0.65 | — | — | |
| SCHEMBL8008332 | 0.64 | — | — | |
| SCHEMBL9473178 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233769-B1 | Imidazole derivatives | SMITHKLINE BEECHAM PLC (GB) | 2007-12-26 | — | — | EP | disclosed |
| US-7189745-B1 | Compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-13 | — | — | US | disclosed |
| US-20070010534-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2007-01-11 | — | — | US | disclosed |
| EP-1233769-A4 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2004-12-29 | — | — | EP | disclosed |
| EP-1233769-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001037835-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC. (GB) | 2001-05-31 | — | — | WO | disclosed |