Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.80 |
| ▸ | CA4 | P22748 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2345927 | 1.00 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL563051 | 1.00 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL2052289 | 1.00 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL19946523 | 1.00 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL41209 | 1.00 | CA1 (0.80) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL28408878 | 0.95 | CA1 (0.73) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL16654487 | 0.95 | CA1 (0.73) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL5278984 | 0.95 | CA1 (0.73) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL28283158 | 0.95 | CA1 (0.73) | CA1CA4LMNATSHRFFAR3 | |
| Acetic Acid SCHEMBL19836 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114335472-A | Cobalt-manganese bimetallic MOFs derivative material and preparation method and application thereof | 燕山大学 | 2022-04-12 | — | — | CN | claimed |
| CN-117903539-A | Fireproof material for crimping-free terminal sheath and preparation method thereof | 国网陕西省电力有限公司陇县供电分公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-114335472-A | Cobalt-manganese bimetallic MOFs derivative material and preparation method and application thereof | 燕山大学 | 2022-04-12 | — | — | CN | disclosed |
| CN-111599603-B | MXene/ZnMnNi LDH van der Waals heterostructure and preparation method and application thereof | 南京理工大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-111599603-A | MXene/ZnMnNi LDH van der Waals heterostructure and preparation method and application thereof | 南京理工大学 | 2020-08-28 | — | — | CN | disclosed |
| CN-110605131-A | Three-dimensional nitrogen-doped carbon-based material loaded bimetallic phosphide bifunctional catalyst and preparation method and application thereof | 韦萍洁 | 2019-12-24 | — | — | CN | disclosed |
| US-7235508-B2 | Metal-incorporated nanoporous nickel phosphate molecular sieve and its preparation method | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2007-06-26 | — | — | US | disclosed |
| US-7166330-B2 | Method for forming a glittering coating film | NIPPON PAINT CO., LTD. (JP) | 2007-01-23 | — | — | US | disclosed |
| US-20060057363-A1 | Method for forming a glittering coating film and glittering coated object | NIPPON PAINT AUTOMOTIVE COATINGS CO., LTD. (JP) | 2006-03-16 | — | — | US | disclosed |
| US-20050043169-A1 | Metal-incorporated nanoporous VSB-5 molecular sieve and its preparation method | KOREA RESEARCH INSTITUTE OF CHEMICAL TECNOLOGY. | 2005-02-24 | — | — | US | disclosed |
| EP-0315189-B1 | Process for producing an alkylenamine by using a mixing oxide catalyst. | Tosoh Corporation (JP) | 1993-02-03 | — | — | EP | disclosed |
| US-5175237-A | Preparation of polyester copolymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-29 | — | — | US | disclosed |
| US-4982003-A | AMINATION CATALYST | TOSOH CORPORATION (JP) | 1991-01-01 | — | — | US | disclosed |
| EP-0315189-A1 | Process for producing an alkylenamine by using a mixing oxide catalyst. | Tosoh Corporation (JP) | 1989-05-10 | — | — | EP | disclosed |
| US-4043984-A | CROSS-LINKING AGENTS | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1977-08-23 | — | — | US | disclosed |