SCHEMBL5484613

SCHEMBL5484613

Cc1cc(C(F)(C(F)(F)F)C(F)(F)F)ccc1N=C1OC(=O)c2c(I)cccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5484609 1.00
SCHEMBL5792424 0.86 CHRM5 (0.31)
SCHEMBL4636560 0.81
SCHEMBL550661 0.80 TACR1 (0.31)
SCHEMBL2889155 0.77 HDAC6 (0.41)
SCHEMBL2889153 0.77 HDAC6 (0.41)
SCHEMBL2887946 0.75 TP53 (0.37)
SCHEMBL2887947 0.75 TP53 (0.37)
SCHEMBL5905908 0.74 PPARD (0.35)
SCHEMBL5905907 0.74 PPARD (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7161032-B2 Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof NIHON NOHYAKU CO., LTD. (JP) 2007-01-09 US disclosed
US-20060167315-A1 Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof NIHON NOHYAKU CO., LTD. (JP) 2006-07-27 US disclosed
WO-2006024523-A1 PHTHALAMIDE DERIVATIVES FOR USE AS INSECTICIDES SYNGENTA PARTICIPATION AG (CH) 2006-03-09 WO disclosed
EP-1544193-A1 SULFONAMIDE DERIVATIVES, INSECTICIDES FOR AGRICULTURAL AND HORTICULTURAL USE, AND USAGE THEREOF Nihon Nohyaku Co., Ltd. (JP) 2005-06-22 EP disclosed