Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 10/20 | 0.67 |
| ▸ | PI4KB | Q9UBF8 | 6/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4521807 | 0.95 | PIK3CG (0.73) | PIK3CGPI4KBALDH1A1MAPTKDM4E | |
| SCHEMBL4525099 | 0.89 | PIK3CG (0.66) | PIK3CGPI4KBALDH1A1MAPTKDM4E | |
| SCHEMBL4513836 | 0.87 | PIK3CG (0.81) | PIK3CGPI4KBALDH1A1MAPTKDM4E | |
| SCHEMBL4519422 | 0.81 | PI4KB (0.79) | PIK3CGPI4KBALDH1A1MAPTKDM4E | |
| SCHEMBL5427675 | 0.78 | PIK3CG (1.00) | PIK3CGPI4KBALDH1A1MAPTKDM4E | |
| SCHEMBL4530751 | 0.77 | MAPT (0.81) | PIK3CGPI4KBALDH1A1MAPTKDM4E | |
| SCHEMBL4528890 | 0.77 | PIK3CG (0.78) | PIK3CGPI4KBALDH1A1MAPTKDM4E | |
| SCHEMBL4528106 | 0.77 | PI4KB (1.00) | PIK3CGPI4KBALDH1A1MAPTKDM4E | |
| SCHEMBL4523621 | 0.77 | PI4KB (0.71) | PIK3CGPI4KBALDH1A1MAPTKDM4E | |
| SCHEMBL4512892 | 0.76 | PIK3CG (1.00) | PIK3CGPI4KBALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709019-B1 | THIAZOLE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS (AN) | 2007-08-08 | — | — | EP | claimed |