Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 12/20 | 0.85 |
| ▸ | AVPR1A | P37288 | 12/20 | 0.85 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.85 |
| ▸ | HTR1A | P08908 | 2/20 | 0.85 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.85 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.85 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.85 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.85 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.85 |
| ▸ | HTR2C | P28335 | 1/20 | 0.85 |
| ▸ | HRH1 | P35367 | 1/20 | 0.85 |
| ▸ | GLP1R | P43220 | 1/20 | 0.85 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.85 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.85 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.85 |
| ▸ | OXTR | P30559 | 1/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tolvaptan SCHEMBL15846692 | 0.92 | AVPR2 (1.00) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| Tolvaptan SCHEMBL29776655 | 0.92 | AVPR2 (1.00) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| Tolvaptan SCHEMBL1650272 | 0.92 | AVPR2 (1.00) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| Tolvaptan SCHEMBL29720852 | 0.92 | AVPR2 (1.00) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL8246087 | 0.92 | AVPR2 (1.00) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| Tolvaptan SCHEMBL31206968 | 0.92 | AVPR2 (1.00) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| Tolvaptan SCHEMBL242421 | 0.92 | AVPR2 (1.00) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| Tolvaptan SCHEMBL29389767 | 0.92 | AVPR2 (1.00) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| Tolvaptan SCHEMBL20769792 | 0.92 | AVPR2 (1.00) | AVPR2AVPR1AABCB11HTR1ACHRM1 | |
| SCHEMBL7346343 | 0.89 | AVPR2 (0.69) | AVPR2AVPR1AABCB11HTR1ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185323-A1 | Method of preparing benzazepines and derivatives thereof | ECOLE POLYTECHNIQUE (FR) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185323-A1 | Method of preparing benzazepines and derivatives thereof | CYP2F1, MAOB, CYP1A2 | AVPR2 1203/4885AVPR1A 2001/4885ABCB11 3034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.