Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 8/20 | 0.69 |
| ▸ | HTR3A | P46098 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | WNT1 | P04628 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1965162 | 1.00 | CHRNA7 (0.69) | CHRNA7HTR3AALDH1A1POLBCSNK2A1 | |
| SCHEMBL1963506 | 1.00 | CHRNA7 (0.69) | CHRNA7HTR3AALDH1A1POLBCSNK2A1 | |
| SCHEMBL1963389 | 0.92 | CHRNA7 (0.69) | CHRNA7HTR3AALDH1A1POLBGSK3B | |
| SCHEMBL1965460 | 0.84 | CHRNA7 (0.76) | CHRNA7HTR3AWNT1DYRK1AHTR3E | |
| SCHEMBL1964878 | 0.84 | CHRNA7 (0.76) | CHRNA7HTR3AWNT1DYRK1AHTR3E | |
| SCHEMBL1963740 | 0.84 | CHRNA7 (0.76) | CHRNA7HTR3AWNT1DYRK1AHTR3E | |
| SCHEMBL1966879 | 0.84 | CHRNA7 (0.76) | CHRNA7HTR3AWNT1DYRK1AHTR3E | |
| SCHEMBL5996566 | 0.84 | CHRNA7 (0.76) | CHRNA7HTR3AWNT1DYRK1AHTR3E | |
| SCHEMBL260705 | 0.83 | CHRNA7 (0.74) | CHRNA7HTR3AGSK3BWNT1DYRK1A | |
| SCHEMBL1963578 | 0.83 | CHRNA7 (0.74) | CHRNA7HTR3AWNT1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007530590-A | — | — | 2007-11-01 | — | — | JP | claimed |
| EP-1735306-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | Memory Pharmaceuticals Corporation (US) | 2006-12-27 | — | — | EP | claimed |
| WO-2005092890-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2005-10-06 | — | — | WO | claimed |