SCHEMBL5486727

SCHEMBL5486727

CCCCCCCCCCCCCCCCCC[SiH2]N(C)C

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
THRB P10828 1/20 0.44
DNM1 Q05193 8/20 0.43
ALDH1A1 P00352 3/20 0.35
LMNA P02545 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HSD17B10 Q99714 1/20 0.35
SLC22A1 O15245 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28262709 1.00 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL28263843 1.00 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL28057837 1.00 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL28335158 1.00 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL28263837 1.00 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL28263834 1.00 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL28263829 1.00 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL28262715 1.00 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL28262808 1.00 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL28262710 1.00 TSHR (0.44) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109075021-A Improved self-assembled monolayer barrier with intermittent air-water exposure 应用材料公司 2018-12-21 CN claimed
CN-114975176-A Chemical delivery chamber for self-assembled monolayer processes 应用材料公司 2022-08-30 CN disclosed
CN-109417042-B Chemical delivery chamber for self-assembled monolayer processes 应用材料公司 2022-05-10 CN disclosed
EP-1596193-B1 Novel stationary phases for use in high-performance liquid chromatography AGILENT TECHNOLOGIES INC (US) 2007-06-20 EP disclosed
CN-1759931-A Novel stationary phases for use in high-performance liquid chromatography AGILENT TECHNOLOGIES INC (US) 2006-04-19 CN disclosed
US-20060076296-A1 Novel stationary phases for use in high-performance liquid chromatography AGILENT TECHNOLOGIES, INC. 2006-04-13 US disclosed
EP-1596193-A1 Novel stationary phases for use in high-performance liquid chromatography Agilent Technologies, Inc. (US) 2005-11-16 EP disclosed