Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CCR6 | P51684 | 2/20 | 0.44 |
| ▸ | GALR2 | O43603 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9593080 | 0.83 | MAPT (0.53) | KDM4EMAPTPOLBSMN1; SMN2NPC1 | |
| SCHEMBL2332293 | 0.82 | MAPT (0.55) | KDM4EMAPTPOLBSMN1; SMN2NPC1 | |
| SCHEMBL8321809 | 0.81 | MAPT (0.54) | KDM4EMAPTPOLBSMN1; SMN2NPC1 | |
| SCHEMBL18149813 | 0.81 | KDM4E (0.58) | KDM4EMAPTSMN1; SMN2NPC1IDO1 | |
| SCHEMBL1313734 | 0.80 | MAPT (0.53) | KDM4EMAPTPOLBSMN1; SMN2NPC1 | |
| SCHEMBL912582 | 0.80 | MAPT (0.59) | KDM4EMAPTPOLBSMN1; SMN2NPC1 | |
| SCHEMBL17979169 | 0.79 | KDM4E (0.56) | KDM4EMAPTPOLBNPC1IDO1 | |
| SCHEMBL5480400 | 0.79 | KDM4E (0.63) | KDM4EMAPTSMN1; SMN2NPC1IDO1 | |
| SCHEMBL31347406 | 0.78 | MAPT (0.51) | KDM4EMAPTPOLBSMN1; SMN2NPC1 | |
| SCHEMBL29076978 | 0.77 | KDM4E (0.53) | KDM4EMAPTSMN1; SMN2IDO1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |