Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 10/20 | 0.35 |
| ▸ | CNR1 | P21554 | 8/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5236556 | 0.91 | GRM5 (0.38) | GRM5CNR2CNR1KCNH2TP53 | |
| SCHEMBL14374399 | 0.88 | GRM5 (0.36) | GRM5CNR2CNR1KCNH2TP53 | |
| SCHEMBL4494735 | 0.84 | GRM5 (0.35) | GRM5CNR2CNR1KCNH2TP53 | |
| SCHEMBL5235784 | 0.83 | TRPV1 (0.38) | GRM5CNR2CNR1KCNH2TP53 | |
| SCHEMBL14374398 | 0.83 | GRM5 (0.34) | GRM5CNR2CNR1KCNH2TP53 | |
| SCHEMBL5240772 | 0.83 | KDM4E (0.39) | GRM5CNR2MAPTKDM4ENPC1 | |
| SCHEMBL14340718 | 0.83 | TRPV1 (0.36) | GRM5CNR2CNR1KCNH2TP53 | |
| SCHEMBL4506761 | 0.83 | GRM5 (0.41) | GRM5CNR2CNR1TP53MAPT | |
| SCHEMBL14374391 | 0.83 | HTR2C (0.35) | GRM5CNR2CNR1KCNH2TP53 | |
| SCHEMBL5460517 | 0.83 | TRPV1 (0.38) | GRM5CNR2CNR1KCNH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244111-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-10-18 | — | — | US | disclosed |
| US-20070244111-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-10-18 | — | — | US | disclosed |
| US-20070244111-A1 | Pyrazolopyrimidines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244111-A1 | Pyrazolopyrimidines | Q6ZSR9, RPLP2, DPYD | GRM5 2135/4885CNR2 2544/4885CNR1 1974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.