Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 15/20 | 0.56 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323706 | 0.88 | PTH1R (0.56) | PTH1R | |
| SCHEMBL5363678 | 0.85 | PTH1R (0.56) | PTH1R | |
| SCHEMBL5326300 | 0.72 | PTH1R (0.48) | PTH1R | |
| SCHEMBL5487298 | 0.72 | PTH1R (0.67) | PTH1R | |
| SCHEMBL5347546 | 0.71 | PTH1R (0.54) | PTH1R | |
| SCHEMBL5356834 | 0.71 | PTH1R (0.42) | PTH1R | |
| SCHEMBL5350284 | 0.68 | PTH1R (0.39) | PTH1R | |
| SCHEMBL5356554 | 0.66 | PTH1R (0.67) | PTH1R | |
| SCHEMBL5350400 | 0.65 | PTH1R (0.51) | PTH1R | |
| SCHEMBL5284221 | 0.64 | PTH1R (0.53) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |