Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL120848 | 0.78 | CD44 (0.61) | CD44GRIN2DGRIN3BGRIN1GRIN2A | |
| Water SCHEMBL29026586 | 0.74 | CD44 (0.58) | CD44GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL168826 | 0.72 | CD44 (0.55) | CD44GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2219302 | 0.72 | CD44 (0.55) | CD44GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5482420 | 0.68 | — | — | |
| SCHEMBL8261003 | 0.68 | CD44 (0.58) | CD44GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL12107994 | 0.67 | AHR (0.56) | CD44GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13176877 | 0.67 | CD44 (0.50) | CD44GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5485036 | 0.65 | CD44 (0.38) | CD44GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16997355 | 0.65 | AHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |