Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 20/20 | 1.00 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.60 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5119067 | 1.00 | AR (1.00) | ARNR3C1PGR | |
| SCHEMBL5495883 | 0.90 | AR (1.00) | ARNR3C1PGR | |
| SCHEMBL5114978 | 0.90 | AR (1.00) | ARNR3C1PGR | |
| SCHEMBL5120028 | 0.85 | AR (0.81) | ARNR3C1PGR | |
| SCHEMBL5122887 | 0.84 | AR (0.72) | ARNR3C1PGR | |
| SCHEMBL5122901 | 0.77 | AR (1.00) | ARNR3C1PGR | |
| SCHEMBL5124349 | 0.76 | AR (1.00) | ARNR3C1PGR | |
| SCHEMBL5122563 | 0.76 | AR (1.00) | ARNR3C1PGR | |
| SCHEMBL5118400 | 0.76 | AR (0.79) | ARNR3C1PGR | |
| SCHEMBL7692659 | 0.75 | AR (1.00) | ARNR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214690-B2 | Tricyclic quinolinone and tricyclic quinoline androgen receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2007-05-08 | — | — | US | claimed |