Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006002 | 0.94 | TYR (0.53) | TYRALOX5TP53CYP3A4MEN1 | |
| SCHEMBL5677856 | 0.86 | TYR (0.62) | TYRALOX5TP53CYP3A4MEN1 | |
| SCHEMBL7631085 | 0.86 | HTR1D (0.44) | TYRALOX5CYP3A4TSHRALDH1A1 | |
| SCHEMBL5678186 | 0.85 | TYR (0.71) | TYRALOX5TP53CYP3A4MEN1 | |
| SCHEMBL5680424 | 0.85 | TYR (0.66) | TYRALOX5TP53CYP3A4MEN1 | |
| SCHEMBL10932407 | 0.83 | TYR (0.59) | TYRALOX5TP53CYP3A4MEN1 | |
| SCHEMBL11698312 | 0.83 | TYR (0.74) | TYRALOX5TP53CYP3A4MEN1 | |
| SCHEMBL27842379 | 0.83 | TYR (0.74) | TYRALOX5TP53CYP3A4MEN1 | |
| SCHEMBL2774201 | 0.83 | TYR (0.59) | TYRALOX5TP53CYP3A4MEN1 | |
| Hexane SCHEMBL11772099 | 0.81 | TYR (0.57) | TYRALOX5TP53CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123571-A1 | Use of a compound in the treatment of sleep disorders | BOOTS HEALTHCARE INTERNATIONAL LIMITED (GB) | 2007-05-31 | — | — | US | disclosed |