SCHEMBL5488569

SCHEMBL5488569

O=C(O)CP(=O)(O)OF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL560738 0.76
SCHEMBL37980 0.74
Hydrochloric Acid SCHEMBL27933376 0.74 MEN1 (0.50)
SCHEMBL4475592 0.74
SCHEMBL2801406 0.74
SCHEMBL29589 0.74
SCHEMBL3457874 0.74
SCHEMBL28695264 0.74 MEN1 (0.50)
SCHEMBL28292374 0.74 MEN1 (0.50)
Water SCHEMBL10936092 0.72 TSHR (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0521752-B1 Process for the preparation of alpha fluorinated acrylates ATOCHEM ELF SA (FR) 1995-03-22 EP claimed
US-5231219-A Process for the preparation of α-fluoroacrylates ELF ATOCHEM S.A. (FR) 1993-07-27 US claimed
WO-2024179405-A1 CLASS OF CINNAMAMIDE DERIVATIVES AND APPLICATION THEREOF 上海交通大学 2024-09-06 WO disclosed
EP-3617182-A1 METHOD FOR PRODUCING ALPHA-FLUOROACRYLIC ACID ESTER DAIKIN INDUSTRIES, LTD. (JP) 2020-03-04 EP disclosed
EP-3617183-A1 PRODUCTION METHOD FOR ALPHA-FLUORO ACRYLIC ACID ESTERS DAIKIN INDUSTRIES, LTD. (JP) 2020-03-04 EP disclosed
US-9950984-B2 Production method for alpha-fluoro acrylic acid esters DAIKIN INDUSTRIES, LTD. (JP) 2018-04-24 US disclosed
US-20170267626-A1 PRODUCTION METHOD FOR ALPHA-FLUORO ACRYLIC ACID ESTERS DAIKIN INDUSTRIES, LTD. (JP) 2017-09-21 US disclosed
US-9738589-B2 Method for producing α-fluoroacrylic acid ester DAIKIN INDUSTRIES, LTD. (JP) 2017-08-22 US disclosed
US-9732027-B2 Production method for alpha-fluoro acrylic acid esters DAIKIN INDUSTRIES, LTD. (JP) 2017-08-15 US disclosed
US-9701614-B2 2017-07-11 US disclosed
US-20160318842-A1 PRODUCTION METHOD FOR ALPHA-FLUORO ACRYLIC ACID ESTERS DAIKIN INDUSTRIES, LTD. (JP) 2016-11-03 US disclosed
EP-1754710-A2 2'-Fluoroncucleosides Emory University (US) 2007-02-21 EP disclosed
US-6348587-B1 PURINE OR PYRIMIDINE BASE DERIVATIVES; ANTICANCER, ANTITUMOR AND ANTIPROLIFERATIVE AGENTS; TREATING HIV AND HEPATITIS EMORY UNIVERSITY 2002-02-19 US disclosed
EP-1058686-A1 2'-FLUORONUCLEOSIDES EMORY UNIVERSITY (US) 2000-12-13 EP disclosed
WO-1999043691-A1 2'-FLUORONUCLEOSIDES EMORY UNIVERSITY (US) 1999-09-02 WO disclosed
EP-0521752-B1 Process for the preparation of alpha fluorinated acrylates ATOCHEM ELF SA (FR) 1995-03-22 EP disclosed
US-5231219-A Process for the preparation of α-fluoroacrylates ELF ATOCHEM S.A. (FR) 1993-07-27 US disclosed
US-5231219-A Process for the preparation of α-fluoroacrylates ELF ATOCHEM S.A. (FR) 1993-07-27 US disclosed
EP-0521752-A1 Process for the preparation of alpha fluorinated acrylates ELF ATOCHEM S.A. (FR) 1993-01-07 EP disclosed
EP-0521752-A1 Process for the preparation of alpha fluorinated acrylates ELF ATOCHEM S.A. (FR) 1993-01-07 EP disclosed