Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 10/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3116176 | 0.93 | LTB4R2 (0.47) | LTB4R2HDAC1HDAC6AGTR1AGTR2 | |
| SCHEMBL3112807 | 0.87 | LTB4R2 (0.47) | LTB4R2HDAC1HDAC6AGTR1AGTR2 | |
| SCHEMBL4609709 | 0.84 | LTB4R2 (0.60) | LTB4R2HDAC1HDAC6ALDH1A1HPGD | |
| SCHEMBL3119670 | 0.84 | LTB4R2 (0.48) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL3116785 | 0.83 | LTB4R2 (0.44) | LTB4R2HDAC1HDAC6AGTR1AGTR2 | |
| SCHEMBL3124786 | 0.82 | LTB4R2 (0.43) | LTB4R2HDAC1HDAC6AGTR1AGTR2 | |
| SCHEMBL3127027 | 0.82 | LTB4R2 (0.45) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL3117096 | 0.82 | HDAC6 (0.56) | LTB4R2HDAC1HDAC6AGTR1AGTR2 | |
| SCHEMBL2964382 | 0.81 | ROCK1 (0.38) | LTB4R2HDAC1HDAC6AGTR1ALDH1A1 | |
| SCHEMBL3124799 | 0.81 | HDAC6 (0.49) | LTB4R2HDAC1HDAC6AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745800-A1 | NOVEL BLT2-MEDIATED DISEASE, AND BLT2 BINDING AGENT AND COMPOUND | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-24 | — | — | EP | disclosed |