Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 4/20 | 0.47 |
| ▸ | GSK3B | P49841 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.45 |
| ▸ | MEN1 | O00255 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 7/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5485565 | 0.81 | KMT2A (0.44) | GSK3AGSK3BKMT2AMEN1MAPT | |
| SCHEMBL5489285 | 0.79 | GSK3A (0.52) | GSK3AGSK3BKMT2AMEN1MAPT | |
| SCHEMBL79670 | 0.76 | KMT2A (0.53) | GSK3AGSK3BKMT2AMEN1MAPT | |
| SCHEMBL5490685 | 0.76 | KMT2A (0.40) | GSK3AGSK3BKMT2AMEN1MAPT | |
| SCHEMBL5484387 | 0.74 | KMT2A (0.49) | GSK3AGSK3BKMT2AMEN1MAPT | |
| SCHEMBL5484818 | 0.74 | GSK3A (0.52) | GSK3AGSK3BKMT2AMEN1MAPT | |
| SCHEMBL5492168 | 0.74 | KMT2A (0.39) | GSK3AGSK3BKMT2AMEN1MAPT | |
| SCHEMBL5492016 | 0.74 | KMT2A (0.39) | GSK3AGSK3BKMT2AMEN1MAPT | |
| SCHEMBL5486725 | 0.74 | KMT2A (0.39) | GSK3AGSK3BKMT2AMEN1MAPT | |
| SCHEMBL9354113 | 0.73 | MAPT (0.47) | GSK3AGSK3BKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7270801-B2 | Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for caspases and other enzymes and the use thereof | CYTOVIA, INC. (US) | 2007-09-18 | — | — | US | disclosed |
| EP-1026988-A4 | NOVEL FLUORESCENT REPORTER MOLECULES AND THEIR APPLICATIONS INCLUDING ASSAYS FOR CASPASES | CYTOVIA INC (US) | 2005-03-30 | — | — | EP | disclosed |
| US-20040191844-A1 | Novel fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for caspases and other enzymes and the use thereof | CYTOVIA, INC. (US) | 2004-09-30 | — | — | US | disclosed |
| US-6759207-B2 | REPORTER COMPOUND FOR USE IN THE DIAGNOSIS, DETECTION AND TREATMENT OF CANCER | CYTOVIA, INC. | 2004-07-06 | — | — | US | disclosed |
| US-20020150885-A1 | Novel fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for caspases and other enzymes and the use thereof | CYTOVIA, INC. | 2002-10-17 | — | — | US | disclosed |
| US-6342611-B1 | BLOCKED RHODAMINE DERIVATIVES | CYTOVIA, INC. | 2002-01-29 | — | — | US | disclosed |
| US-6335429-B1 | COMPOUND INCLUDING SUBSTRATE FOR ENZYME AND RHODAMINE DYE; DRUG SCREENING FOR ANTICARCINOGENIC AGENTS | CYTOVIA, INC. | 2002-01-01 | — | — | US | disclosed |
| EP-1026988-A1 | NOVEL FLUORESCENT REPORTER MOLECULES AND THEIR APPLICATIONS INCLUDING ASSAYS FOR CASPASES | Cytovia, Inc. (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999018856-A1 | NOVEL FLUORESCENT REPORTER MOLECULES AND THEIR APPLICATIONS INCLUDING ASSAYS FOR CASPASES | CYTOVIA, INC. (US) | 1999-04-22 | — | — | WO | disclosed |