Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2875141 | 0.96 | TSHR (0.50) | TSHRTHRBLMNASLC22A1SLC22A2 | |
| SCHEMBL809486 | 0.93 | TSHR (0.57) | TSHRTHRBLMNASLC22A1DNM1 | |
| Potassium Ion SCHEMBL5672140 | 0.93 | TSHR (0.47) | TSHRTHRBLMNASLC22A1SLC22A2 | |
| SCHEMBL5715699 | 0.93 | TSHR (0.57) | TSHRTHRBLMNASLC22A1DNM1 | |
| Ammonia Solution, Strong SCHEMBL4761998 | 0.93 | TSHR (0.47) | TSHRTHRBLMNASLC22A1SLC22A2 | |
| SCHEMBL7751336 | 0.93 | TSHR (0.47) | TSHRTHRBLMNASLC22A1SLC22A2 | |
| SCHEMBL5715695 | 0.93 | TSHR (0.57) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL15799696 | 0.93 | TSHR (0.47) | TSHRTHRBLMNASLC22A1SLC22A2 | |
| SCHEMBL5716311 | 0.93 | TSHR (0.57) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL10799739 | 0.93 | TSHR (0.57) | TSHRTHRBLMNASLC22A1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730156-A1 | PROCESS FOR PRODUCING TETRAKIS(FLUOROARYL)BORATE SALTS | ALBEMARLE CORPORATION (US) | 2006-12-13 | — | — | EP | claimed |
| WO-2005105816-A1 | PROCESS FOR PRODUCING TETRAKIS (FLUOROARYL) BORATE-SALTS | ALBEMARLE CORPORATION (US) | 2005-11-10 | — | — | WO | claimed |
| WO-2001040235-A1 | PROCESS FOR PRODUCING DI-(TETRAKIS(FLUOROARYL)BORATO)-MAGNESIUM-SALTS AND CLATHRATES | ALBEMARLE CORPORATION (US) | 2001-06-07 | — | — | WO | claimed |
| US-6169208-B1 | Process for producing a magnesium di[tetrakis(Faryl)borate] and products therefrom | ALBEMARLE CORPORATION | 2001-01-02 | — | — | US | claimed |
| US-20070197831-A1 | Process for producing tetrakis(faryl)borate-salts | LEE JOHN Y | 2007-08-23 | — | — | US | disclosed |
| EP-1730156-A1 | PROCESS FOR PRODUCING TETRAKIS(FLUOROARYL)BORATE SALTS | ALBEMARLE CORPORATION (US) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005105816-A1 | PROCESS FOR PRODUCING TETRAKIS (FLUOROARYL) BORATE-SALTS | ALBEMARLE CORPORATION (US) | 2005-11-10 | — | — | WO | disclosed |
| WO-2001040235-A1 | PROCESS FOR PRODUCING DI-(TETRAKIS(FLUOROARYL)BORATO)-MAGNESIUM-SALTS AND CLATHRATES | ALBEMARLE CORPORATION (US) | 2001-06-07 | — | — | WO | disclosed |