Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 17/20 | 0.55 |
| ▸ | GRM5 | P41594 | 13/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12975576 | 0.86 | GRM1 (0.70) | GRM1GRM5 | |
| SCHEMBL2893797 | 0.85 | GRM1 (0.58) | GRM1GRM5ALDH1A1SMN1; SMN2HRH1 | |
| SCHEMBL2892061 | 0.85 | GRM1 (0.74) | GRM1GRM5ALDH1A1SMN1; SMN2HRH1 | |
| SCHEMBL27666676 | 0.79 | GRM1 (0.74) | GRM1GRM5ALDH1A1SMN1; SMN2 | |
| SCHEMBL2891696 | 0.79 | GRM1 (0.57) | GRM1GRM5ALDH1A1SMN1; SMN2 | |
| SCHEMBL2885105 | 0.79 | GRM1 (0.73) | GRM1GRM5ALDH1A1SMN1; SMN2 | |
| SCHEMBL2888969 | 0.77 | GRM1 (0.72) | GRM1GRM5ALDH1A1SMN1; SMN2 | |
| SCHEMBL2893976 | 0.76 | GRM1 (0.77) | GRM1GRM5 | |
| SCHEMBL2893262 | 0.76 | GRM1 (0.73) | GRM1GRM5ALDH1A1SMN1; SMN2 | |
| SCHEMBL2893240 | 0.75 | GRM1 (0.71) | GRM1GRM5ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764362-A1 | BIARYL DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-03-21 | — | — | EP | disclosed |