SCHEMBL5489726

SCHEMBL5489726

FC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
KDM4E B2RXH2 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
USP2 O75604 1/20 0.32
MAPT P10636 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1827978 1.00 TSHR (0.42) TSHRKDM4ETDP1USP2MAPT
SCHEMBL1829371 1.00 TSHR (0.42) TSHRKDM4ETDP1USP2MAPT
SCHEMBL1825532 1.00 TSHR (0.42) TSHRKDM4ETDP1USP2MAPT
SCHEMBL1824897 1.00 TSHR (0.42) TSHRKDM4ETDP1USP2MAPT
SCHEMBL1824498 1.00 TSHR (0.42) TSHRKDM4ETDP1USP2MAPT
SCHEMBL16687343 1.00 TSHR (0.42) TSHRKDM4ETDP1USP2MAPT
SCHEMBL5492824 1.00 TSHR (0.42) TSHRKDM4ETDP1USP2MAPT
SCHEMBL5487202 1.00 TSHR (0.42) TSHRKDM4ETDP1USP2MAPT
Water SCHEMBL10544296 0.96 TSHR (0.40) TSHRKDM4ETDP1USP2MAPT
SCHEMBL498059 0.96 KDM4E (0.43) TSHRKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070196763-A1 Method of forming laminated resist DAIKIN INDUSTRIES, LTD. 2007-08-23 US disclosed
EP-1686425-A1 METHOD FOR FORMING MULTILAYER RESIST Daikin Industries, Ltd. (JP) 2006-08-02 EP disclosed