Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 20/20 | 0.55 |
| ▸ | GRM5 | P41594 | 4/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2892787 | 0.92 | GRM1 (0.55) | GRM1GRM5HRH1TMEM97 | |
| SCHEMBL2891852 | 0.89 | GRM1 (0.51) | GRM1GRM5HRH1TMEM97 | |
| SCHEMBL12975671 | 0.89 | GRM1 (0.60) | GRM1GRM5HRH1TMEM97 | |
| SCHEMBL12975607 | 0.86 | GRM1 (0.69) | GRM1GRM5HRH1TMEM97 | |
| SCHEMBL2885501 | 0.86 | GRM1 (0.69) | GRM1GRM5HRH1TMEM97 | |
| SCHEMBL2890559 | 0.79 | GRM1 (0.78) | GRM1GRM5HRH1TMEM97 | |
| SCHEMBL2890753 | 0.79 | GRM1 (0.61) | GRM1GRM5HRH1TMEM97 | |
| SCHEMBL2889708 | 0.77 | GRM1 (0.59) | GRM1GRM5HRH1TMEM97 | |
| SCHEMBL2885810 | 0.77 | GRM1 (0.54) | GRM1GRM5HRH1TMEM97 | |
| SCHEMBL2893262 | 0.76 | GRM1 (0.73) | GRM1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764362-A1 | BIARYL DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-03-21 | — | — | EP | disclosed |
| EP-1764362-A1 | BIARYL DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-03-21 | — | — | EP | disclosed |