Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 20/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5125307 | 1.00 | AR (0.58) | ARNR3C1PGR | |
| SCHEMBL5123747 | 0.90 | AR (0.57) | ARNR3C1PGR | |
| SCHEMBL5123735 | 0.90 | AR (0.57) | ARNR3C1PGR | |
| SCHEMBL5125424 | 0.90 | AR (0.55) | ARNR3C1PGR | |
| SCHEMBL5128999 | 0.90 | AR (0.61) | ARNR3C1PGR | |
| SCHEMBL5124234 | 0.89 | AR (0.57) | ARNR3C1PGR | |
| SCHEMBL5129186 | 0.88 | AR (0.56) | ARNR3C1PGR | |
| SCHEMBL5119368 | 0.88 | AR (0.59) | ARNR3C1PGR | |
| SCHEMBL5489173 | 0.88 | AR (0.59) | ARNR3C1PGR | |
| SCHEMBL5124380 | 0.88 | AR (0.52) | ARNR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214690-B2 | Tricyclic quinolinone and tricyclic quinoline androgen receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2007-05-08 | — | — | US | disclosed |