Paeoniflorin

Paeoniflorin

SCHEMBL549033

C[C@@]12C[C@@]3(O)O[C@@H](O1)[C@]1(COC(=O)c4ccccc4)[C@H]3C[C@@]12O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC22A1 O15245 1/20 0.88
GRK2 P25098 1/20 0.80
SYNJ2 O15056 3/20 0.49
MAOB P27338 1/20 0.39
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
HSP90AA1 P07900 1/20 0.34
PTPN1 P18031 1/20 0.33
LGALS9 O00182 1/20 0.33
LGALS1 P09382 1/20 0.33
LGALS3 P17931 1/20 0.33
LGALS7; LGALS7B P47929 1/20 0.33
SELP P16109 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Paeoniflorin SCHEMBL15236857 1.00 SLC22A1 (0.88) SLC22A1GRK2SYNJ2MAOBALDH1A1
Paeoniflorin SCHEMBL17880403 1.00 SLC22A1 (0.88) SLC22A1GRK2SYNJ2MAOBALDH1A1
Paeoniflorin SCHEMBL13615628 1.00 SLC22A1 (0.88) SLC22A1GRK2SYNJ2MAOBALDH1A1
Paeoniflorin SCHEMBL20009472 1.00 SLC22A1 (0.88) SLC22A1GRK2SYNJ2MAOBALDH1A1
Paeoniflorin SCHEMBL24935593 1.00 SLC22A1 (0.88) SLC22A1GRK2SYNJ2MAOBALDH1A1
Paeoniflorin SCHEMBL14088840 1.00 SLC22A1 (0.88) SLC22A1GRK2SYNJ2MAOBALDH1A1
Paeoniflorin SCHEMBL24927267 1.00 SLC22A1 (0.88) SLC22A1GRK2SYNJ2MAOBALDH1A1
Paeoniflorin SCHEMBL29396890 1.00 SLC22A1 (0.88) SLC22A1GRK2SYNJ2MAOBALDH1A1
Paeoniflorin SCHEMBL22649040 1.00 SLC22A1 (0.88) SLC22A1GRK2SYNJ2MAOBALDH1A1
Paeoniflorin SCHEMBL7625329 0.99 SLC22A1 (0.87) SLC22A1GRK2SYNJ2MAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10834 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12635710-B2 Methods of using formaldehyde-free antimicrobial compositions in animal by-product compositions EASTMAN CHEMICAL COMPANY (US) 2026-05-26 US claimed
CN-122084809-A Feature map detection method of detumescence particles or intermediate extract thereof and application thereof 2026-05-26 CN claimed
CN-122075510-A High-activity epiglottis blood stasis removing decoction effective part and application thereof in preparing cough relieving pharmaceutical composition 2026-05-26 CN claimed
CN-122075636-A Fingerprint spectrum standardized traditional Chinese medicine composition for relieving myopia 2026-05-26 CN claimed
WO-2026097395-A1 USE OF IDO1 INHIBITOR ALBIFLORIN OR/AND PAEONIFLORIN IN IMMUNOTHERAPY FOR CANCER COMORBID WITH DEPRESSION 张作光 2026-05-15 WO claimed
CN-122030527-A Beverage with function of relieving muscle soreness after exercise and preparation method thereof 一杯本草(西安)健康科技有限公司 2026-05-15 CN claimed
WO-2026097393-A1 USE OF ALBIFLORIN FOR PREVENTING AND TREATING DEPRESSION COMORBID WITH METABOLIC SYNDROME AND DEPRESSION COMORBID WITH TYPE II DIABETES 张作光 2026-05-15 WO claimed
CN-122031591-A Traditional Chinese medicine composition for treating chronic pelvic inflammatory disease, preparation method and detection method thereof 湖南省妇幼保健院 2026-05-15 CN claimed
CN-122005686-A External application medicine for subacute thyroiditis acute stage and preparation method thereof 广东省中医院海南医院 2026-05-12 CN claimed
CN-122005693-A Application of Jiaweidanzhi Xiaoyao powder or extract thereof in preparation of medicines for treating depression complicated with ulcerative colitis 河南中医药大学 2026-05-12 CN claimed
US-20020058805-A1 Process for extracting glycoside using an aqueous two-phase system INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2002-05-16 US claimed
US-20020038020-A1 Process for extracting glycoside using an aqueous two-phase system INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2002-03-28 US claimed
EP-1188442-A2 Cinnamomi and poria composition, method to prepare the same and uses thereof Xiao, Wei (CN) 2002-03-20 EP claimed
CN-1339298-A Compound traditional medicine with piperine for increasing biological utilization of paeoniflorin and its preparing method TANG XIAOHAI (CN) 2002-03-13 CN claimed
CN-1338259-A White peony root's total glycoside injection NANFANG PHARMACEUTICAL FACTORY (CN) 2002-03-06 CN claimed
CN-1054074-C Compound ginkgo leaf prepn. and its prepn. method LIU XINGKAI (CN) 2000-07-05 CN claimed
CN-1196954-A Compound ginkgo leaf prepn. and its prepn. method LIU XINGJIE (CN) 1998-10-28 CN claimed
EP-0742012-A2 Pharmaceutical composition containing substance inhibiting HSP47 production Kureha Chemical Industry Co., Ltd. (JP) 1996-11-13 EP claimed
CN-1100651-A Chinese herbal prepn. for curing chronic gastroenteritis and peptic gastric ulcer PHARMACEUTICAL SCIENCE & TECH (CN) 1995-03-29 CN claimed
CN-1077386-A A kind of Chinese patent medicine for the treatment of angina pectoris PLA AIRFORCE GENERAL HOSPITAL (CN) 1993-10-20 CN claimed