⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10158781 | 0.72 | — | — | |
| SCHEMBL9240341 | 0.70 | — | — | |
| SCHEMBL17060212 | 0.69 | — | — | |
| SCHEMBL6750294 | 0.68 | — | — | |
| SCHEMBL6750302 | 0.68 | — | — | |
| SCHEMBL15557295 | 0.68 | — | — | |
| SCHEMBL6752203 | 0.67 | — | — | |
| SCHEMBL6752205 | 0.67 | — | — | |
| SCHEMBL13531697 | 0.63 | — | — | |
| SCHEMBL10644390 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496943-A4 | OLIGOMERIC COMPOUNDS HAVING MODIFIED PHOSPHATE GROUPS | ISIS PHARMACEUTICALS INC (US) | 2007-05-23 | — | — | EP | disclosed |
| US-20060003952-A1 | Oligomeric compounds having modified phosphate groups | ISIS PHARMACEUTICALS, INC. (US) | 2006-01-05 | — | — | US | disclosed |
| EP-1496943-A2 | OLIGOMERIC COMPOUNDS HAVING MODIFIED PHOSPHATE GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087115-A2 | OLIGOMERIC COMPOUNDS HAVING MODIFIED PHOSPHATE GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 2003-10-23 | — | — | WO | disclosed |
| US-20030190626-A1 | Phosphorothioate monoester modified oligomers | ISIS PHARMACEUTICALS, INC. | 2003-10-09 | — | — | US | disclosed |