Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.76 |
| ▸ | CA12 | O43570 | 1/20 | 0.73 |
| ▸ | CA1 | P00915 | 1/20 | 0.73 |
| ▸ | CA2 | P00918 | 1/20 | 0.73 |
| ▸ | CA4 | P22748 | 1/20 | 0.73 |
| ▸ | CA6 | P23280 | 1/20 | 0.73 |
| ▸ | CA7 | P43166 | 1/20 | 0.73 |
| ▸ | TPMT | P51580 | 1/20 | 0.73 |
| ▸ | CA9 | Q16790 | 1/20 | 0.73 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.73 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.64 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.62 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122418 | 0.98 | TSHR (0.78) | TSHRCA12CA1CA2CA4 | |
| SCHEMBL21614005 | 0.97 | TSHR (0.76) | TSHRCA12CA1CA2CA4 | |
| SCHEMBL30683868 | 0.95 | TSHR (0.69) | TSHRCA12CA1CA2CA4 | |
| SCHEMBL89386 | 0.95 | TSHR (0.69) | TSHRCA12CA1CA2CA4 | |
| SCHEMBL8085474 | 0.95 | TSHR (0.78) | TSHRCA12CA1CA2CA4 | |
| SCHEMBL30622523 | 0.92 | TSHR (0.69) | TSHRCA12CA1CA2CA4 | |
| SCHEMBL1750327 | 0.92 | TSHR (0.74) | TSHRCA12CA1CA2CA4 | |
| SCHEMBL1545237 | 0.92 | TSHR (0.69) | TSHRCA12CA1CA2CA4 | |
| SCHEMBL19970616 | 0.92 | TSHR (0.69) | TSHRCA12CA1CA2CA4 | |
| SCHEMBL2329752 | 0.92 | TSHR (0.74) | TSHRCA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210380743-A1 | ULTRAVIOLET-RAY ABSORBING POLYMER, FORMATION RESIN COMPOSITION, AND FORMED BODY | TOYO INK SC HOLDINGS CO., LTD. (JP) | 2021-12-09 | — | — | US | disclosed |
| US-9950996-B2 | Bio-based aromatic diisocyanates for preparation of polyurethanes | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-04-24 | — | — | US | disclosed |
| US-20170369427-A1 | BIO-BASED AROMATIC DIISOCYANATES FOR PREPARATION OF POLYURETHANES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-12-28 | — | — | US | disclosed |
| US-7265105-B2 | Pyrrolobenzodiazepines | SPIROGEN LIMITED (GB) | 2007-09-04 | — | — | US | disclosed |
| US-7265105-B2 | Pyrrolobenzodiazepines | SPIROGEN LIMITED (GB) | 2007-09-04 | — | — | US | disclosed |
| US-20060148788-A1 | Pyrrolobenzodiazepines | SPIROGEN LIMITED (GB) | 2006-07-06 | — | — | US | disclosed |
| US-7067511-B2 | Pyrrolobenzodiazepines | SPIROGEN LIMITED (GB) | 2006-06-27 | — | — | US | disclosed |
| EP-1109812-B1 | PYRROLOBENZODIAZEPINES | SPIROGEN LTD (GB) | 2005-05-04 | — | — | EP | disclosed |
| US-20030195196-A1 | Pyrrolobenzodiazepines | SPIROGEN LIMITED (GB) | 2003-10-16 | — | — | US | disclosed |
| EP-1109811-B1 | PYRROLOBENZODIAZEPINES | SPIROGEN LTD (GB) | 2003-08-06 | — | — | EP | disclosed |
| EP-1193270-A2 | Pyrrolobenzodiazepines | Spirogen Limited (GB) | 2002-04-03 | — | — | EP | disclosed |
| EP-0637613-B1 | RESIN COMPOSITION | MITSUBISHI GAS CHEMICAL CO (JP) | 2000-10-25 | — | — | EP | disclosed |
| US-6110578-A | STRUCTURAL UNIT DERIVED FROM HYDROXYCARBOXYLIC ACID, A STRUCTURAL UNIT DERIVED FROM MOLECULAR WEIGHT INCREASING AGENT AND/OR A STRUCTURAL UNIT DERIVED FROM POLYMERIZATION CATALYST DEACTIVATOR. | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-08-29 | — | — | US | disclosed |
| US-5543474-A | BLEND OF A AROMATIC POLYAMIDEIMIDE COPOLYMER AND A POLYESTER | MITSUBISHI GAS COMPANY, INC. (JP) | 1996-08-06 | — | — | US | disclosed |
| EP-0637613-A1 | RESIN COMPOSITION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1995-02-08 | — | — | EP | disclosed |
| EP-0282052-B1 | POLYPHENYLENE ETHER RESIN COMPOSITION | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1992-10-14 | — | — | EP | disclosed |
| EP-0148774-B1 | POLYPHENYLENE ETHER RESIN COMPOSITION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1991-05-22 | — | — | EP | disclosed |
| US-4879360-A | POLYESTER, EPOXIDIZED POLYBUTADIENE | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1989-11-07 | — | — | US | disclosed |
| US-4614773-A | AROMATIC POLYESTERS EPOXY RESINS, UNSATURATED ACIDS; SOLVENT RESISTANCE | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1986-09-30 | — | — | US | disclosed |
| EP-0148774-A2 | Polyphenylene ether resin composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1985-07-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369427-A1 | BIO-BASED AROMATIC DIISOCYANATES FOR PREPARATION OF POLYURETHANES | PAH, ALKBH3, AOC3 | TSHR 4834/4885CA12 2797/4885CA1 2869/4885 |
| US-20060148788-A1 | Pyrrolobenzodiazepines | HCRTR2, MCHR2, CHRM5 | TSHR 425/4885CA12 3939/4885CA1 4526/4885 |
| US-20030195196-A1 | Pyrrolobenzodiazepines | CNR2, CNR1, HRH3 | TSHR 526/4885CA12 471/4885CA1 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.