SCHEMBL5492262

SCHEMBL5492262

O=C1N=c2cccc(CP(=O)(O)O)c2=NC1=O

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 2/20 0.45
GRIN2D O15399 2/20 0.43
GRIN3B O60391 2/20 0.43
GRIN1 Q05586 2/20 0.43
GRIN2A Q12879 2/20 0.43
GRIN2B Q13224 2/20 0.43
GRIN2C Q14957 2/20 0.43
GRIN3A Q8TCU5 2/20 0.43
PGK1 P00558 3/20 0.42
PGK2 P07205 3/20 0.42
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1079466 0.74
SCHEMBL8053801 0.69 ACP3 (0.65) ACP3GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL29707862 0.69 ACP3 (0.65) ACP3GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL9174132 0.66 ACP3 (0.57) ACP3GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL21638770 0.66 ACP3 (0.52) ACP3GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL2420219 0.65 ACP3 (0.55) ACP3GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL8018526 0.65 TSHR (0.38)
SCHEMBL4836284 0.65 ACP3 (0.55) ACP3GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL9164686 0.65 ACP3 (0.66) ACP3GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL14732169 0.64 ACP3 (0.46) ACP3GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070161592-A1 Method of treating fear ZHUO MIN 2007-07-12 US disclosed