SCHEMBL5492354

SCHEMBL5492354

CCC(=O)C(C)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31298801 0.97
SCHEMBL509870 0.78 CYP2C9 (0.40)
SCHEMBL2703448 0.78
SCHEMBL2720085 0.77
SCHEMBL9043621 0.77
SCHEMBL11465282 0.77
SCHEMBL11000641 0.75
SCHEMBL11724354 0.75
SCHEMBL13520926 0.75
SCHEMBL11469807 0.75 CACNA2D1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5475155-A Reacting an alpha-haloketone with a phenolic-hydroxyl containing compound and a strong protonic acid; neutralization; dehydrohalogenation; dealkylation THE DOW CHEMICAL COMPANY (US) 1995-12-12 US claimed
WO-1995015301-A1 PREPARATION OF 4,4'-DIHYDROXY-ALPHA-ALKYLSTILBENES AND 4,4'-DIHYDROXY-ALPHA, ALPHA'-DIALKYLSTILBENES THE DOW CHEMICAL COMPANY (US) 1995-06-08 WO claimed
EP-0370391-A2 Process for the preparation of 4,5-dichloro-6-ethyl pyrimidine LONZA AG (CH) 1990-05-30 EP claimed
JP-55162749-A None JP disclosed
CN-118151489-B Photosensitive resin composition, photosensitive dry film and application thereof 湖南初源新材料股份有限公司 2024-08-13 CN disclosed
CN-118151489-A Photosensitive resin composition, photosensitive dry film and application thereof 湖南初源新材料股份有限公司 2024-06-07 CN disclosed
CN-113861137-B Method for synthesizing furan compound by one-step reaction of ketone and alpha chloroketone 重庆医科大学 2023-08-15 CN disclosed
CN-113861137-A Method for synthesizing furan compound by one-step reaction of ketone and alpha chloroketone 重庆医科大学 2021-12-31 CN disclosed
WO-2021240429-A1 BENZOFURAN AND BENZOPYRAN DIHYDROOROTATE DEHYDROGENASE INHIBITORS JANSSEN BIOTECH, INC. (US) 2021-12-02 WO disclosed
WO-2017099821-A1 COMPOSITIONS AND METHODS FOR INHIBITING CBP80 BINDING TO PGCI FAMILY OF CO-ACTIVATORS UNIVERSITY OF ROCHESTER (US) 2017-06-15 WO disclosed
US-8501781-B2 Heteroarylpiperidine and -piperazine derivatives BAYER CROPSCIENCE AG (DE) 2013-08-06 US disclosed
US-4240983-A HALOGENATION BAYER AKTIENGESELLSCHAFT (DE) 1980-12-23 US disclosed
JP-S55162749-A NOVEL PROCESS FOR PREPARATION OF 3-ANILINO-3-METHYLBUTAN- 2-ONE CHISSO CORP 1980-12-18 JP disclosed
EP-0005810-B1 METHOD FOR THE PREPARATION OF ORGANIC FLUORO COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1980-11-12 EP disclosed
EP-0005810-A1 Method for the preparation of organic fluoro compounds HOECHST AKTIENGESELLSCHAFT (DE) 1979-12-12 EP disclosed
US-4153606-A Process for the production of thiazoline-(3) compounds DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1979-05-08 US disclosed
US-4081480-A ORGANOLEPTIC, FLAVORS, ODORS, ENHANCEMENT INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-03-28 US disclosed
US-4064280-A Flavoring with α-oxy(oxo)mercaptans INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-12-20 US disclosed
US-4064278-A FRUIT AND VEGETABLE FOODSTUFFS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-12-20 US disclosed
US-4024289-A Flavoring with α-oxy(oxo)mercaptans INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-05-17 US disclosed