Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23346807 | 0.77 | GAA (0.33) | GAADYRK1ACDK9KDM1ARCOR1 | |
| SCHEMBL5172490 | 0.77 | KDM1A (0.33) | GAADYRK1ACDK9KDM1ARCOR1 | |
| SCHEMBL5173083 | 0.77 | KDM1A (0.33) | GAAKDM1ARCOR1 | |
| SCHEMBL5040102 | 0.77 | KDM1A (0.43) | GAADYRK1ACDK9KDM1ARCOR1 | |
| SCHEMBL5172412 | 0.61 | KDM1A (0.34) | GAAKDM1ARCOR1 | |
| SCHEMBL5039658 | 0.60 | KDM1A (0.46) | GAAKDM1ARCOR1 | |
| SCHEMBL5036385 | 0.59 | — | — | |
| SCHEMBL23815084 | 0.59 | — | — | |
| SCHEMBL4415644 | 0.57 | CYP3A4 (0.42) | DYRK1ACDK9 | |
| SCHEMBL5039952 | 0.57 | KDM1A (0.41) | GAAKDM1ARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276089-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-10-02 | — | — | US | disclosed |
| US-20060042025-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | NOXELL CORPORATION | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060042025-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, KDM5A, KDM5C | GAA 3692/4885DYRK1A 2383/4885CDK9 1178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.