Sugi Predict

Sugi Predict / Compounds / SCHEMBL5492869

SCHEMBL5492869

SCHEMBL5492869

Cc1ccc2c(Cl)cccc2c1Cl

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 6/20 0.59
▸ CYP2A6 P11509 5/20 0.59
▸ NR4A2 P43354 2/20 0.46
▸ TYMS P04818 2/20 0.40
▸ ALDH1A1 P00352 3/20 0.37
▸ TSHR P16473 3/20 0.35
▸ CYP3A4 P08684 2/20 0.35
▸ HPGD P15428 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ ADRA2A P08913 1/20 0.35
▸ PARP1 P09874 1/20 0.34
▸ LMNA P02545 1/20 0.33
▸ PLA2G7 Q13093 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ NFKB1 P19838 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30569673 1.00 CYP1A2 (0.59) CYP1A2CYP2A6NR4A2TYMSALDH1A1
SCHEMBL11506343 0.83 AXL (0.41) CYP1A2CYP2A6NR4A2ALDH1A1TSHR
SCHEMBL292927 0.78 CYP1A2 (0.54) CYP1A2CYP2A6NR4A2TYMSALDH1A1
SCHEMBL28883426 0.78 CYP1A2 (0.54) CYP1A2CYP2A6NR4A2TYMSALDH1A1
SCHEMBL4629602 0.78 CYP1A2 (0.54) CYP1A2CYP2A6NR4A2TYMSALDH1A1
SCHEMBL6109650 0.78 TRPV1 (0.45) CYP1A2CYP2A6ALDH1A1TSHRCYP3A4
SCHEMBL3269018 0.78 CYP1A2 (0.54) CYP1A2CYP2A6NR4A2TYMSALDH1A1
SCHEMBL29932445 0.78 CYP2A6 (0.68) CYP1A2CYP2A6NR4A2TYMSTSHR
SCHEMBL20356025 0.78 CYP2A6 (0.68) CYP1A2CYP2A6NR4A2TYMSTSHR
SCHEMBL7676818 0.78 CYP1A2 (0.68) CYP1A2CYP2A6NR4A2TYMSALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117405643-A AI-based intelligent fluorescence detection technical method and system 贵州国芯生物科技有限公司 2024-01-16 — — CN claimed
CN-114425311-B Porous adsorption material based on reuse of alcohol-soluble waste in polyphenyl ether production process and synthesis method thereof 浙江工业大学 2023-09-08 — — CN claimed
CN-117405643-A AI-based intelligent fluorescence detection technical method and system 贵州国芯生物科技有限公司 2024-01-16 — — CN disclosed
CN-114425311-B Porous adsorption material based on reuse of alcohol-soluble waste in polyphenyl ether production process and synthesis method thereof 浙江工业大学 2023-09-08 — — CN disclosed
US-7227027-B2 Carbazole derivative and its use in electroluminescent devices TSINGHUA UNIVERSITY (CH) 2007-06-05 — — US disclosed
US-20050127826-A1 Carbazole derivative and its use in electroluminescent devices BEIJING VISIONOX TECHNOLOGY CO., LTD. (CN) 2005-06-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050127826-A1 Carbazole derivative and its use in electroluminescent devices OCIAD1, OCIAD2, EED CYP1A2 1378/4885CYP2A6 3812/4885NR4A2 860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.