Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 1.00 |
| ▸ | CCR7 | P32248 | 4/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5498108 | 1.00 | CXCR2 (1.00) | CXCR2CCR7 | |
| SCHEMBL5497377 | 0.92 | CXCR2 (0.86) | CXCR2CCR7 | |
| SCHEMBL5492950 | 0.91 | CXCR2 (0.83) | CXCR2CCR7 | |
| SCHEMBL5498209 | 0.90 | CXCR2 (0.82) | CXCR2CCR7 | |
| SCHEMBL5492987 | 0.89 | CXCR2 (0.80) | CXCR2CCR7 | |
| SCHEMBL5998455 | 0.89 | CXCR2 (0.80) | CXCR2CCR7 | |
| SCHEMBL5499203 | 0.84 | CXCR2 (0.73) | CXCR2CCR7 | |
| SCHEMBL5495370 | 0.84 | CXCR2 (0.73) | CXCR2CCR7 | |
| SCHEMBL5191224 | 0.82 | CXCR2 (0.69) | CXCR2CCR7 | |
| SCHEMBL5499371 | 0.82 | CXCR2 (0.69) | CXCR2CCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328319-B1 | 7-AMINO-2-ALKYLTHIOPTERIDIN-4-YL-AMINES FOR THE TREATMENT OF CHEMOKINE-RELATED DISEASES | ASTRAZENECA AB (SE) | 2007-01-03 | — | — | EP | claimed |