SCHEMBL5493451

SCHEMBL5493451

O=C(OCCO)/C(=C\C1=CCCC1)C1=CCCC1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 2/20 0.35
HDAC2 Q92769 2/20 0.35
HDAC8 Q9BY41 2/20 0.35
HDAC6 Q9UBN7 2/20 0.35
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
GSTP1 P09211 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1502494 1.00 HDAC4 (0.35) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL5831856 0.84 HDAC4 (0.36) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL1502492 0.83 HDAC4 (0.35) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL4908235 0.80 GSTP1 (0.34) GSTP1
Ethylene Glycol SCHEMBL5493455 0.80 HDAC4 (0.39) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL27987047 0.80 HDAC4 (0.42) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL352867 0.78 HDAC3 (0.31) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL29066043 0.77 HDAC4 (0.37) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL300627 0.76 HDAC4 (0.43) HDAC4HDAC2HDAC8HDAC6HDAC3
SCHEMBL93924 0.76 HDAC4 (0.43) HDAC4HDAC2HDAC8HDAC6HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1373331-A4 THERMALLY CURED UNDERLAYER FOR LITHOGRAPHIC APPLICATION FUJIFILM ELECTRONIC MATERIALS (US) 2007-01-17 EP claimed
US-6924339-B2 Thermally cured underlayer for lithographic application ARCH SPECIALTY CHEMICALS, INC. (US) 2005-08-02 US claimed
EP-1373331-A2 THERMALLY CURED UNDERLAYER FOR LITHOGRAPHIC APPLICATION ARCH SPECIALTY CHEMICALS, INC. (US) 2004-01-02 EP claimed
US-20030204035-A1 Thermally cured underlayer for lithographic application ARCH SPECIALTY CHEMICALS INC. 2003-10-30 US claimed
US-6610808-B2 Thermally cured underlayer for lithographic application ARCH SPECIALTY CHEMICALS, INC. 2003-08-26 US claimed
US-20020173594-A1 Thermally cured underlayer for lithographic application ARCH SPECIALTY CHEMICALS, INC. (US) 2002-11-21 US claimed
WO-2002073307-A2 THERMALLY CURED UNDERLAYER FOR LITHOGRAPHIC APPLICATION ARCH SPECIALTY CHEMICALS, INC. (US) 2002-09-19 WO claimed