⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1142602 | 1.00 | KCNH2 (0.52) | — | |
| SCHEMBL25042763 | 1.00 | KCNH2 (0.52) | — | |
| Ammonia Solution, Strong SCHEMBL3924276 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL28286507 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL1643106 | 0.97 | — | — | |
| SCHEMBL4323972 | 0.88 | KCNH2 (0.44) | — | |
| SCHEMBL10296875 | 0.88 | KCNH2 (0.44) | — | |
| SCHEMBL16584661 | 0.88 | KCNH2 (0.44) | — | |
| SCHEMBL23119845 | 0.88 | KCNH2 (0.44) | — | |
| SCHEMBL14371896 | 0.88 | KCNH2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 699 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117983168-B | Charging intelligent regulation's cyclopropylethyl amide production reation kettle | 江苏飞宇医药科技股份有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-117983168-A | Charging intelligent regulation's cyclopropylethyl amide production reation kettle | 江苏飞宇医药科技股份有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-117398960-B | Cyclopropylethyl amide production reaction kettle with quantitative feeding structure | 江苏飞宇医药科技股份有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-117398960-A | Cyclopropylethyl amide production reaction kettle with quantitative feeding structure | 江苏飞宇医药科技股份有限公司 | 2024-01-16 | — | — | CN | claimed |
| EP-4293016-A1 | QUINAZOLINE-BASED COMPOUND, COMPOSITION, AND APPLICATION OF QUINAZOLINE-BASED COMPOUND | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2023-12-20 | — | — | EP | claimed |
| WO-2023070483-A1 | PROCESSES OF MAKING 3-FLUORO-5- ( ( (1R, 2S, 2aS) -1, 2, 3, 3, 4, 4-HEXAFLUORO-2A-HYDROXY-2, 2A, 3, 4-TETRAHYDRO-1H-CYCLOPENTA [CD] INDEN-7-YL) -OXY) -BENZONITRILE AND POLYMORPHS THEREOF | NIKANG THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | claimed |
| WO-2023060431-A1 | PROCESSES OF MAKING 3-FLUORO-5- ( ( (1S, 2AR) -1, 3, 3, 4, 4-PENTAFLUORO-2A-HYDROXY-2, 2A, 3, 4-TETRAHYDRO-1H-CYCLOPENTA [CD] INDEN-7-YL) OXY) -BENZONITRILE AND POLYMORPHS THEREOF | NIKANG THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | claimed |
| WO-2023060458-A1 | PROCESSES OF MAKING 3-FLUORO-5- ( ( (1S, 2AR) -1, 3, 3, 4, 4-PENTAFLUORO-2A-HYDROXY-2, 2A, 3, 4-TETRAHYDRO-1H-CYCLOPENTA [CD] INDEN-7-YL) OXY) -BENZONITRILE AND POLYMORPHS THEREOF | NIKANG THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | claimed |
| CN-115109036-A | Quinazoline compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-111269131-B | Process for preparing cyclopropyl ethyl amide by taking tri-n-propylamine as acid acceptor | 江苏飞宇医药科技股份有限公司 | 2021-12-28 | — | — | CN | claimed |
| WO-2004092164-A1 | CYCLIC AMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF INFLAMMATION-RELATED DISORDERS MEDIATED BY BRADYKININ | AMGEN, INC. (US) | 2004-10-28 | — | — | WO | claimed |
| US-20040116687-A1 | oligonucleotides having reduced internucleotide charge and enhanced nuclease resistance | AGILENT TECHNOLOGIES, INC. | 2004-06-17 | — | — | US | claimed |
| EP-1334111-A2 | PHOSPHINOAMIDITE CARBOXYLATES AND ANALOGS THEREOF IN THE SYNTHESIS OF OLIGONUCLEOTIDES HAVING REDUCED INTERNUCLEOTIDE CHARGE | Dellinger, Douglas J. (US) | 2003-08-13 | — | — | EP | claimed |
| WO-2002032912-A2 | PHOSPHINOAMIDITE CARBOXYLATES AND ANALOGS THEREOF IN THE SYNTHESIS OF OLIGONUCLEOTIDES HAVING REDUCED INTERNUCLEOTIDE CHARGE | DELLINGER DOUGLAS J (US) | 2002-04-25 | — | — | WO | claimed |
| US-5684148-A | NUCLEOSIDES AND POLYNUCLEOTIDES AS FLUORESCENT AGENTS FOR MEDICAL DIAGNOSIS | COMPETITIVE TECHNOLOGIES, INC. (US) | 1997-11-04 | — | — | US | claimed |
| US-5218103-A | Nucleoside thiophosphoramidites | UNIVERSITY PATENTS, INC. (US) | 1993-06-08 | — | — | US | claimed |
| EP-0378615-A4 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | — | 1992-04-08 | — | — | EP | claimed |
| WO-1991004983-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | UNIVERSITY PATENTS, INC. (US) | 1991-04-18 | — | — | WO | claimed |
| EP-0378615-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | COMPETITIVE TECHNOLOGIES INC. (US) | 1990-07-25 | — | — | EP | claimed |
| WO-1989011486-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | UNIVERSITY PATENTS, INC. (US) | 1989-11-30 | — | — | WO | claimed |