Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5118678 | 1.00 | AR (0.40) | ARCDK1TRPA1 | |
| SCHEMBL5114827 | 0.89 | AR (0.53) | ARCDK1TRPA1 | |
| SCHEMBL5114835 | 0.89 | AR (0.53) | ARCDK1TRPA1 | |
| SCHEMBL5122002 | 0.86 | AR (0.55) | ARCDK1 | |
| SCHEMBL5124748 | 0.86 | AR (0.55) | ARCDK1 | |
| SCHEMBL5116557 | 0.85 | AR (0.45) | AR | |
| SCHEMBL5123270 | 0.84 | AR (0.56) | AR | |
| SCHEMBL5486825 | 0.84 | AR (0.55) | ARCDK1TRPA1 | |
| SCHEMBL5115984 | 0.84 | AR (0.55) | ARCDK1TRPA1 | |
| SCHEMBL5123257 | 0.82 | AR (0.42) | ARCDK1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214690-B2 | Tricyclic quinolinone and tricyclic quinoline androgen receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2007-05-08 | — | — | US | disclosed |