⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20776323 | 0.87 | — | — | |
| SCHEMBL7793301 | 0.85 | KDM1A (0.31) | — | |
| SCHEMBL20776342 | 0.79 | — | — | |
| SCHEMBL22084028 | 0.78 | — | — | |
| SCHEMBL10988854 | 0.74 | — | — | |
| SCHEMBL22249331 | 0.74 | — | — | |
| SCHEMBL22249332 | 0.74 | — | — | |
| SCHEMBL24497274 | 0.73 | — | — | |
| SCHEMBL14701161 | 0.73 | — | — | |
| SCHEMBL10988849 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430733-A | Bimetallic catalyst based on acylhydrazone pyrene skeleton, and preparation method and application thereof | 万华化学集团股份有限公司 | 2024-01-23 | — | — | CN | claimed |
| US-7169759-B1 | Tetrapeptide inhibitors of β-secretase | ELAN PHARMACEUTICALS, INC. (US) | 2007-01-30 | — | — | US | claimed |
| US-20050182138-A1 | Dipeptide inhibitors of beta-secretase | ELAN PHARMACEUTICALS, INC. | 2005-08-18 | — | — | US | claimed |
| US-6864240-B1 | Dipeptide inhibitors of β-secretase | ELAN PHARMACEUTICALS, INC. (US) | 2005-03-08 | — | — | US | claimed |
| EP-1192177-A1 | STATINE-DERIVED TETRAPEPTIDE INHIBITORS OF BETA-SECRETASE | Elan Pharmaceuticals, Inc. (US) | 2002-04-03 | — | — | EP | claimed |
| WO-2000077030-A1 | STATINE-DERIVED TETRAPEPTIDE INHIBITORS OF BETA-SECRETASE | ELAN PHARMACEUTICALS, INC. (US) | 2000-12-21 | — | — | WO | claimed |
| CN-117430733-A | Bimetallic catalyst based on acylhydrazone pyrene skeleton, and preparation method and application thereof | 万华化学集团股份有限公司 | 2024-01-23 | — | — | CN | disclosed |