Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL238451 | 0.96 | KDM4E (0.34) | KDM4EALDH1A1HRH4HRH3 | |
| Hydrochloric Acid SCHEMBL13859413 | 0.92 | KDM4E (0.38) | KDM4EALDH1A1HRH4HRH3 | |
| Hydrochloric Acid SCHEMBL6661072 | 0.88 | KDM4E (0.32) | KDM4EALDH1A1HRH4HRH3 | |
| SCHEMBL5035490 | 0.85 | CYP2C19 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL19287116 | 0.85 | CYP2C19 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL4908355 | 0.85 | CYP2C19 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL4915897 | 0.85 | CYP2C19 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL27228689 | 0.82 | HRH4 (0.32) | KDM4EALDH1A1HRH4HRH3 | |
| SCHEMBL27228618 | 0.82 | KDM4E (0.30) | KDM4EALDH1A1 | |
| SCHEMBL3318414 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130052349-A1 | ORGANOMETALLIC COMPOUNDS | PRAXAIR TECHNOLOGY, INC. | 2013-02-28 | — | — | US | claimed |
| US-20070299274-A1 | Organometallic compounds | PRAXAIR TECHNOLOGY, INC. | 2007-12-27 | — | — | US | claimed |
| US-20130052349-A1 | ORGANOMETALLIC COMPOUNDS | PRAXAIR TECHNOLOGY, INC. | 2013-02-28 | — | — | US | disclosed |
| US-20130047890-A1 | ORGANOMETALLIC COMPOUNDS | PRAXAIR TECHNOLOGY, INC. | 2013-02-28 | — | — | US | disclosed |
| US-8318966-B2 | Organometallic compounds | PRAXAIR TECHNOLOGY, INC. (US) | 2012-11-27 | — | — | US | disclosed |
| US-20070299274-A1 | Organometallic compounds | PRAXAIR TECHNOLOGY, INC. | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299274-A1 | Organometallic compounds | NR1H3, NR1H2, NR1I3 | KDM4E 1155/4885ALDH1A1 2787/4885HRH4 41/4885 |
| US-20130052349-A1 | ORGANOMETALLIC COMPOUNDS | NR1H3, NR1H2, NR1I3 | KDM4E 1155/4885ALDH1A1 2787/4885HRH4 41/4885 |
| US-20130047890-A1 | ORGANOMETALLIC COMPOUNDS | NR1H3, NR1H2, NR1I3 | KDM4E 1155/4885ALDH1A1 2787/4885HRH4 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.