Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.48 |
| ▸ | F10 | P00742 | 10/20 | 0.48 |
| ▸ | PLG | P00747 | 4/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.47 |
| ▸ | PROC | P04070 | 1/20 | 0.47 |
| ▸ | TMPRSS11D | O60235 | 4/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | HPN | P05981 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | MASP2 | O00187 | 1/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | FCER2 | P06734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14628111 | 1.00 | F2 (0.48) | F2F10PLGKLKB1PROC | |
| Hydrochloric Acid SCHEMBL307828 | 0.99 | F2 (0.48) | F2F10PLGKLKB1PROC | |
| SCHEMBL17366096 | 0.89 | F2 (0.57) | F2F10PLGKLKB1PROC | |
| SCHEMBL20117496 | 0.89 | F2 (0.57) | F2F10PLGKLKB1PROC | |
| SCHEMBL16843096 | 0.89 | F2 (0.57) | F2F10PLGKLKB1PROC | |
| SCHEMBL17366095 | 0.89 | F2 (0.57) | F2F10PLGKLKB1PROC | |
| SCHEMBL12514665 | 0.87 | F2 (0.46) | F2F10PLGTMPRSS11DPLAU | |
| Acetic Acid SCHEMBL30541187 | 0.87 | F2 (0.55) | F2F10PLGKLKB1PROC | |
| Hydrochloric Acid SCHEMBL6923723 | 0.86 | F2 (0.41) | F2F10PLGKLKB1PROC | |
| SCHEMBL8290835 | 0.85 | F2 (0.59) | F2F10PLGKLKB1PROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453852-B1 | SELECTIVE UROKINASE INHIBITORS | WILEX AG (DE) | 2007-01-17 | — | — | EP | claimed |
| EP-1453852-A2 | SELECTIVE UROKINASE INHIBITORS | Wilex AG (DE) | 2004-09-08 | — | — | EP | claimed |
| WO-2003053999-A2 | SELECTIVE ARYLGUANIDINE PEPTIDES AS UROKINASE INHIBITORS | WILEX AG (DE) | 2003-07-03 | — | — | WO | claimed |
| EP-1453852-B1 | SELECTIVE UROKINASE INHIBITORS | WILEX AG (DE) | 2007-01-17 | — | — | EP | disclosed |
| EP-1453852-A2 | SELECTIVE UROKINASE INHIBITORS | Wilex AG (DE) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003053999-A2 | SELECTIVE ARYLGUANIDINE PEPTIDES AS UROKINASE INHIBITORS | WILEX AG (DE) | 2003-07-03 | — | — | WO | disclosed |