Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 2/20 | 0.30 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5039658 | 0.75 | KDM1A (0.46) | KDM1ARCOR1MAPTGAATHRB | |
| SCHEMBL5172412 | 0.72 | KDM1A (0.34) | KDM1ARCOR1MAPTGAATHRB | |
| SCHEMBL5173083 | 0.71 | KDM1A (0.33) | KDM1ARCOR1MAPTGAAFTO | |
| SCHEMBL5173801 | 0.70 | MAPT (0.37) | KDM1ARCOR1MAPTGAATHRB | |
| SCHEMBL5172605 | 0.67 | SMN1; SMN2 (0.33) | KDM1ARCOR1MAPTGAATHRB | |
| SCHEMBL5170746 | 0.63 | MAPT (0.37) | KDM1ARCOR1MAPTTHRBSMN1; SMN2 | |
| SCHEMBL5039834 | 0.59 | KDM1A (0.43) | KDM1ARCOR1MAPTGAATHRB | |
| SCHEMBL5171222 | 0.59 | — | — | |
| SCHEMBL5172490 | 0.59 | KDM1A (0.33) | KDM1ARCOR1MAPTGAA | |
| SCHEMBL5040102 | 0.59 | KDM1A (0.43) | KDM1ARCOR1MAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276089-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-10-02 | — | — | US | claimed |
| US-20060042025-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | NOXELL CORPORATION | 2006-03-02 | — | — | US | claimed |
| US-7276089-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-10-02 | — | — | US | disclosed |
| US-20060042025-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | NOXELL CORPORATION | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060042025-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, KDM5A, KDM5C | KDM1A 366/4885RCOR1 3357/4885MAPT 1271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.