SCHEMBL5495903

SCHEMBL5495903

O=C(CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)N1CCN(N2CCCNC2)CC1

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5495229 0.85 F10 (0.74) F10
SCHEMBL3899037 0.84 F10 (0.67) F10
SCHEMBL1156966 0.83 F10 (0.71) F10
SCHEMBL2857500 0.78 F10 (1.00) F10
SCHEMBL948929 0.78 F10 (0.67) F10
SCHEMBL3899082 0.76 F10 (0.67) F10
SCHEMBL15959336 0.76 F10 (0.67) F10
SCHEMBL947718 0.75 F10 (0.68) F10
SCHEMBL13303260 0.74 F10 (0.71) F10
SCHEMBL2858958 0.74 F10 (0.77) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1748985-A1 CYCLIC AMIDE DERIVATIVES, AND THEIR PRODUCTION AND USE AS ANTITHROMBOTIC AGENTS Takeda Pharmaceutical Company Limited (JP) 2007-02-07 EP disclosed
WO-2005113504-A1 CYCLIC AMIDE DERIVATIVES, AND THEIR PRODUCTION AND USE AS ANTITHROMBOTIC AGENTS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-12-01 WO disclosed