Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052397 | 0.89 | PARP1 (0.94) | PARP1CYP1A2 | |
| SCHEMBL4046195 | 0.88 | PARP1 (1.00) | PARP1CYP1A2 | |
| SCHEMBL4054679 | 0.86 | PARP1 (0.69) | PARP1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL5412704 | 0.81 | PARP1 (0.70) | PARP1CYP1A2 | |
| SCHEMBL4049898 | 0.81 | PARP1 (0.76) | PARP1CYP1A2 | |
| SCHEMBL4047260 | 0.79 | PARP1 (0.80) | PARP1CYP1A2 | |
| SCHEMBL31468374 | 0.78 | PARP1 (0.49) | PARP1 | |
| Trifluoroacetic Acid SCHEMBL5417866 | 0.77 | PARP1 (0.67) | PARP1CYP1A2 | |
| SCHEMBL4047902 | 0.77 | PARP1 (0.76) | PARP1CYP1A2 | |
| SCHEMBL4048006 | 0.77 | PARP1 (1.00) | PARP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144669-A1 | PYRAZOLO[1,5-A]QUINAZOLIN-5(4H)-ONES AS INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-12-21 | — | — | WO | disclosed |