Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOK | Q9UQ07 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | NCF1 | P14598 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.43 |
| ▸ | MTOR | P42345 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiophene SCHEMBL5496494 | 1.00 | MOK (0.52) | MOKMAPTNCF1CYP1A2CYP3A4 | |
| SCHEMBL1385200 | 0.95 | MOK (0.55) | MOKMAPTNCF1CYP1A2CYP3A4 | |
| SCHEMBL1385196 | 0.95 | MOK (0.55) | MOKMAPTNCF1CYP1A2CYP3A4 | |
| SCHEMBL5090188 | 0.87 | MTOR (0.53) | MOKMAPTKDM4ERAB9ANPC1 | |
| SCHEMBL5090197 | 0.87 | MTOR (0.53) | MOKMAPTKDM4ERAB9ANPC1 | |
| SCHEMBL1386140 | 0.86 | MOK (0.54) | MOKMAPTNCF1CYP1A2CYP3A4 | |
| SCHEMBL1386142 | 0.86 | MOK (0.54) | MOKMAPTNCF1CYP1A2CYP3A4 | |
| SCHEMBL5096010 | 0.85 | BCHE (0.50) | MOKMAPTNCF1KDM4EMEN1 | |
| SCHEMBL5096014 | 0.85 | BCHE (0.50) | MOKMAPTNCF1KDM4EMEN1 | |
| SCHEMBL1381775 | 0.85 | MOK (0.51) | MOKMAPTNCF1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748987-A2 | 2-PROPENE-1-ONES AS HSP 70 INDUCERS | Torrent Pharmaceuticals Ltd (IN) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005097746-A2 | 2-PROPENE-1-ONES AS HSP 70 INDUCERS | TORRENT PHARMACEUTICALS LTD (IN) | 2005-10-20 | — | — | WO | disclosed |