Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495154 | 0.90 | XIAP (0.53) | XIAPDPP4DPP8DPP9KMT2A | |
| SCHEMBL8296681 | 0.90 | XIAP (0.53) | XIAPDPP4DPP8DPP9KMT2A | |
| SCHEMBL29689606 | 0.86 | XIAP (0.53) | ELANEXIAPDPP4DPP8DPP9 | |
| SCHEMBL30563254 | 0.80 | ELANE (0.44) | ELANEXIAPDPP4KMT2A | |
| SCHEMBL22546193 | 0.80 | XIAP (0.49) | ELANEXIAPDPP4DPP8DPP9 | |
| SCHEMBL31195362 | 0.79 | ACE (0.48) | ELANEXIAP | |
| SCHEMBL3388723 | 0.78 | XIAP (0.44) | XIAPDPP4DPP8DPP9 | |
| SCHEMBL12272846 | 0.78 | XIAP (0.44) | XIAPDPP4DPP8DPP9 | |
| SCHEMBL27149740 | 0.78 | XIAP (0.44) | XIAPDPP4DPP8DPP9 | |
| SCHEMBL30052896 | 0.78 | XIAP (0.64) | ELANEXIAPDPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166579-B2 | Prodrugs of DP IV-inhibitors | PROSIDION LIMITED (GB) | 2007-01-23 | — | — | US | claimed |